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Selected Recent Publications

Full list of publications on Pubmed

M.I. Garcia, J.J. Chen, D. Boehning, Genetically encoded calcium indicators for studying long-term calcium dynamics during apoptosis, Cell Calcium December 31, (2016) doi:


M.I Garcia, D. Boehning, Cardiac inositol 1,4,5-trisphosphate receptors, BBA-Molecular Cell Research Nov. 22, (2016) doi: 


M.I. Garcia, A. Karlstaedt, J. Amione-Guerra, K.A. Youker, H. Taegtmeyer, D. Boehning Functionally redundant control of cardiac hypertrophy by inositol 1,4,5-trisphosphate receptors,  bioRxiv Sept. 13, (2016) doi: (preprint)


A.M. Akimzhanov, D. Boehning Rapid and Transient Palmitoylation Of The Tyrosine Kinase Lck Mediates Fas Signaling, PNAS Sept. 8th (2015) [Epub ahead of print] doi: 10.1073/pnas.1509929112 PMCID: PMC4586849


S. C. Hedgepeth, M. I. Garcia, L. E. Wagner II, A. M. Rodriguez, S. V. Chintapalli, R. R. Snyder, G. D.V. Hankins, B. R. Henderson, K. M. Brodie, D. I. Yule, D. B. van Rossum, and D. Boehning The BRCA1 Tumor Suppressor Binds to Inositol 1,4,5-Trisphosphate Receptors to Stimulate Apoptotic Calcium Release, JBC, February 2 (2015) [Epub ahead of print] doi: 10.1074/jbc.M114.611186


M.A. Borahay, G.S. Kilic, C. Yallampalli, R.R. Snyder, G.D.V. Hankins, A. Al-Hendy, D. Boehning Simvastatin Potently Induces Calcium-Dependent Apoptosis of Human Leiomyoma Cells, JBC, October 30 (2014) [Epub ahead of print] doi:10.1074/jbc.M114.583575 ​


C. Fos, S. Becart, A.J. Balancio, D. Boehning, Altman, A. Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP3 receptor 1 promotes Ca2+ signaling in T cells, Science Signaling, Sep 30; 7(345):ra93. DOI: 10.1126/scisignal.2005565 (2014). ​


X. Wang, A. El Ayadi, D. Boehning, J.A. Putkey. The Calmodulin Regulator Protein, PEP-19, Sensitizes ATP-induced Ca2+ Release, JBC Nov 30. [Epub ahead of print] (2012).

A.M. Akimzhanov, J.M. Barral, D. Boehning. Caspase-3 cleavage of the inositol 1,4,5-trisphosphate receptor does not contribute to apoptotic calcium release.Cell Calcium, (2012).

A. El Ayadi, S. Stieren, J.M. Barral, A.F. Oberhauser, D. Boehning. Purification and aggregation of the APP intracellular domain. J. Vis. Exp.(66), e4204 10.3791/4204, DOI : 10.3791/4204 (2012).

A. El Ayadi, E.S. Stieren, J.M. Barral, D. Boehning.  Ubiquilin-1 regulates APP maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688.  PNAS doi:10.1073/pnas.1206786109 Epub July 30 (2012).
S.L. Clark, A.M. Rodriguez, Snyder, R.R., Hankins, G.D.V., D. Boehning. Structure-function of the tumor suppressor BRCA1. Computational and Structural Biotechnology Journal, 1(1): e201204005. doi: (2012).
D. Boehning, J.M. Barral, Protein quality control in Alzheimer's disease: the contentious role of ubiquilin-1. Future Neurology, 7(1): 5-8 (2012).

Stieren, E.S., El Ayadi, A., Xiao, Y., Siller, E., Landsverk, M.L., Oberhauser, A.O., Barral, J.M., Boehning, D. Ubiquilin-1 is a molecular chaperone for amyloid precursor protein. Journal of Biological Chemistry, Oct 14;286(41):35689-98 (2011).
A.M. Akimzhanov and D. Boehning. IP3R function in cells of the immune system. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling. doi: 10.1002/wmts.27 (2011).
Jeschke, M.G., Boehning, D. Endoplasmic reticulum stress and insulin resistance post trauma: similarities to type 2 diabetes. Journal of Cellular and Molecular Medicine, Accepted manuscript online: 3 AUG 2011 10:58PM EST | DOI: 10.1111/j.1582-4934.2011.01405.x
Akimzhanov, A.M., Boehning, D. Monitoring Dynamic Changes In Mitochondrial Calcium Levels During Apoptosis Using A Genetically Encoded Calcium Sensor. JoVE. 50., doi: 10.3791/2579 (2011).
D. Boehning; Molecular Architecture Of the Inositol 1,4,5-trisphosphate Receptor Pore. In Serysheva, I. (ed.) Current Topics In Membranes, 66, 191-207 (2010).
A. Akimzhanov, X. Wang, J. Sun, D. Boehning. T cell receptor complex is essential for Fas signal transduction. PNAS 107(34): 15105-15110 (2010).